Produse pentru reacții cutanate (2)

StratiCELL offers product objectivation studies on a wide range of skin models, including cell cultures in monolayer (keratinocytes, fibroblasts, melanocytes, adipocytes, sebocytes, sensory neurons, endothelial cells, etc.), human reconstituted epidermis and finally, human skin explants. All these 2D or 3D models can be derived from primary, hiPS-derived cells or from particular conditions (i.e. from psoriatic or AD patients), and can be stimulated or exposed to stress factors as required. Our skin models are manufactured in-house and are the results of more than 15 years of R&D innovations. Skin cells in monolayer cultures In vitro reconstituted human epidermis Ex vivo skin explants

StratiCELL offers evaluation of the effectiveness of active ingredients, formulations and / or finished products in protecting the skin against oxidative stress and molecular damages induced by different light rays. Examples of assays performed at StratiCELL: DNA damage (cyclobutane pyrimidine dimers) Stress response (p53, Heat Shock Proteins, NRF-2 pathway) Apoptosis (caspase-3) and Sunburn cells Inflammation (Langerhans cells phenotype) Protein oxidation Elastin degradation